Patient Education Blog

Homocysteine and MTHFR Mutations – A Summary for Patients

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Stephan Moll, MD writes… A plain language summary for patients and interested public about homocysteine and the MTHFR mutations and their relevance in respect to blood clots was  published today in the journal Circulation (link here).

Reference:  Moll S, Varga EA.  Homocysteine and MTHFR Mutations. Circulation. 2015;132:e6-e.



Patient Volunteers Needed for Guideline Development

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Stephan Moll, MD writes…  The American Society of Hematology (ASH) is embarking on a program to develop clinically useful guidelines on the best management of patients with deep vein thrombosis or pulmonary embolism.  ASH appropriately desires input from patients for the development of these guidelines.  Any interested patient please see this letter from ASH explaining the goals of the project and what is needed.

Last updated:  July 1st, 2015

Clotting Disorders (Thrombophilia): Who Should Be Tested? What To Test?

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Stephan Moll, MD writes… A publication today in the journal Vascular Medicine discusses - for patients and family members – (a) in which patient with blood clots (DVT, PE) to consider testing for a clotting disorder, (b) what tests might be appropriate to do, (c) how the test results influence management with blood thinners, (d) what birth control methods are safe in women with history of blood clots or a clotting disorder,  and (e) in which family members to consider thrombophilia testing (link here for the article).


Disclosures:  None

Last updated: April 1st, 2015



DVT and PE Prevention when Admitted to the Hospital

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Stephan Moll, MD writes (on12/5/2014)… Prevention of DVT and PE in patients who are in the hospital is important.  Hospitals are required to have mechanisms in place that guarantee that patients at risk for DVT and PE get appropriate prophylaxis [reference].  We have developed at the University of North Carolina (UNC) a guidance document (link here; UNC VTE prophylaxis guidance document) as a resource for our doctors to assist in making decisions on which patients to give what type of DVT and PE prophylaxis.  We are making this document available for other doctors and hospitals, to use it as is or modify it as needed.

Recommendations provided in this document are a reflection of current guidelines, clinical evidence, and UNC institutional initiatives.  Patients may look at this document to see what kind of DVT prophylaxis might be appropriate in certain situations, such as surgeries; and they should discuss appropriate prophylaxis with their physicians.  However, this document is not intended to replace individual patient evaluation and management decisions.


Joint Commission VTE measures (link here)

Disclosures: None

Last updated: Dec 5th, 2014