Patient Education Blog

Posts Tagged ‘clotting disorder’

FAQ: Should I or my family members be tested for genetic causes of blood clotting?

| Clotting disorder - thrombophilia, Uncategorized | Comments Off on FAQ: Should I or my family members be tested for genetic causes of blood clotting?

Some persons have either a genetic (inherited) or acquired predisposition to develop blood clots, known as a thrombophilia or clotting disorder. There are several types of thrombophilias which contribute to varying degrees of clot risk. Read the rest of this entry »

Pregnancy Loss and Clotting Disorders

| Antiphospholipid antibodies, Antithrombin deficiency, Clotting disorder - thrombophilia, Factor V Leiden, Protein C deficiency, Protein S deficiency, Prothrombin 20210 mutation, Therapy, Women and blood clots | 8 Comments »

How common is pregnancy loss? What are the causes?

Pregnancy loss (= miscarriage) in the general population is common. Most losses occur in the first trimester. As many as 5 % of women have 2 or more early losses; 1-2 % have 3 or more early losses [ref 1]. Well established risk factors for pregnancy loss are: (a) advanced age of the mother, (b) anatomic abnormalities of the uterus (such as fibroids), (c) chromosome abnormalities of fetus, the mother or the father, (d) underlying diseases of the mother (endocrine, immunologic), (e) maternal hormonal unbalances.  The acquired clotting disorder called “antiphospholipid antibody syndrome” is also a risk factor for pregnancy loss. The role of inherited clotting disorders (= thrombophilias) contributing to pregnancy loss is less clear. Read the rest of this entry »

Sinus and Cerebral Vein Thrombosis

| Clots in unusual locations | 38 Comments »

Stephan Moll, MD writes…


Sinus and cerebral vein clots are uncommon. They can lead to severe headaches, confusion, and stroke-like symptoms. They may lead to bleeding into the surrounding brain tissues. The clot can be triggered by infections of the ear, face, or neck, by estrogen use and pregnancy, and can be caused by inherited and acquired clotting disorders. The diagnosis is, unfortunately, sometimes initially missed by health care professionals, as a plain CT or MRI of the head can be normal. Read the rest of this entry »